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APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 662-662 doi: 10.15302/J-FASE-2021408

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Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells

Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kaifeng Xu, Guangbiao Zhou

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 252-263 doi: 10.1007/s11684-021-0837-6

Abstract: BaP induces an aryl hydrocarbon receptor (AhR)-dependent upregulation of the ubiquitin E3 ligase Skp2

Keywords： SARS-CoV-2     tobacco smoke     benzo(a)pyrene     ACE2     Skp2    

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APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: MdSIZ1 is a SUMO (small ubiquitin-like modifier) E3 ligase that promotes SUMO binding to substrate proteins

Keywords： apple / drought tolerance / gene expression / MdSIZ1    

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Identification of an E3 ligase-encoding gene

Yanfei Zhang, Xinchun Zhao, Yongchun Zhou, Min Wang, Guangbiao Zhou

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 318-326 doi: 10.1007/s11684-019-0708-6

Abstract: In order to unveil ubiquitin pathway genes (UPGs) that are essential for non-small cell lung cancer (We found that silencing of one of the candidates, that encodes an E3 ubiquitin ligase essential for

Keywords： RFWD3     NSCLC     prognosis     tobacco smoke    

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mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?

Shi-Yong Sun

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 221-231 doi: 10.1007/s11684-020-0812-7

Abstract: Beyond early findings on induced activation of PI3K/Akt, MEK/ERK, and Mnk/eIF4E survival signaling pathwayscompromise the efficacy of rapalog-based cancer therapy, recent findings on the essential role of GSK3

Keywords： mTOR     cancer therapy     resistance     GSK3     protein degradation     E3 ubiquitin ligase     PD-L1    

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APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Baohua CHU, Jia SUN, Huan DANG, Ziqing MA, Shuang ZHAO, Qingmei GUAN, Xuewei LI

Frontiers of Agricultural Science and Engineering   Pages 247-261 doi: 10.15302/J-FASE-2021388

Abstract: MdSIZ1 is a SUMO (small ubiquitin-like modifier) E3 ligase that promotes SUMO binding to substrate proteins

Keywords： apple     drought tolerance     gene expression     MdSIZ1    

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Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 97-104 doi: 10.15302/J-FASE-2018248

Abstract:

Plant nucleotide binding domain and leucine-rich repeat (NLR) receptors recognize pathogen effectors directly or indirectly and mediate innate immune responses. NLR-mediated immunity also has direct impacts on plant growth and development, as well as yield and survival. The levels of NLR proteins are therefore intricately controlled in plants to balance defense responses and other processes. In recent years, the ubiquitination-26S proteasome system and the HSP90 chaperones have emerged as having key functions in the regulation of NLR stability. The N-end rule pathway of protein degradation is also directly linked to NLR stability. Recent progress in the regulation of NLR stability and turnover is summarized here, focusing on the key components and pathways.

Keywords： E3 ubiquitin ligase     degradation     nucleotide-binding leucine-rich repeat receptor     plant immunity     proteasome    

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Design of GPRS Data Terminal Based on S3C2410

Sun Xueyong

Strategic Study of CAE 2007, Volume 9, Issue 12,   Pages 94-96

Abstract: hardware structure and working process of the embedded Internetconnected platform, which regards S3C2410as kernel and SIM100-E as GPRS communication module.

Keywords： GPRS；embedded Internet；S3C2410；SIM100-E    

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A cooperative heterogeneous vehicular clustering framework for efficiency improvement Research Articles

Iftikhar Ahmad, Rafidah Md Noor, Zaheed Ahmed, Umm-e-Habiba, Naveed Akram, Fausto Pedro García Márquez

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 9,   Pages 1247-1259 doi: 10.1631/FITEE.2000260

Abstract: Heterogeneous ing integrates multiple types of communication networks to work efficiently for various vehicular applications. One popular form of heterogeneous network is the integration of long-term evolution (LTE) and dedicated short-range communication. The of such a network infrastructure and the non- involved in sharing cost/data are potential problems to solve. A ing framework is one solution to these problems, but the framework should be formally verified and validated before being deployed in the real world. To solve these issues, first, we present a heterogeneous framework, named destination and interest-aware clustering, for ing that integrates vehicular ad hoc networks with the LTE network for improving road traffic efficiency. Then, we specify a model system of the proposed framework. The model is formally verified to evaluate its performance at the functional level using a model checking technique. To evaluate the performance of the proposed framework at the micro-level, a heterogeneous simulation environment is created by integrating state-of-the-art tools. The comparison of the simulation results with those of other known approaches shows that our proposed framework performs better.

Keywords： 车辆集群；异构性；协同；形式验证；系统模型    

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Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

Collaborative Research Group, De-Pei LIU PhD, Lai-Yuan WANG PhD, Jing CHEN MD, MSc, Jiang HE MD, PhD, Cashell E.RAO PhD, Charles GU PhD, James E. HIXSON PhD, Chung-Shiuan CHEN MS8, Paul K.

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 59-66 doi: 10.1007/s11684-010-0015-8

Abstract: ) in the adducin 1 alpha (ADD1) and guanine nucleotide binding protein (G protein) beta polypeptide 3(GNB3) genes and systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) responses to

Keywords： potassium     potassium sensitivity     adducin 1 alpha (ADD1)     guanine nucleotide binding protein beta polypeptide 3(GNB3)    

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A novel hybrid cryptosystem based on DQFrFT watermarking and 3D-CLM encryption for healthcare services Research Article

SOLIMAN, Fathi E.

Frontiers of Information Technology & Electronic Engineering 2023, Volume 24, Issue 7,   Pages 1045-1061 doi: 10.1631/FITEE.2200372

Abstract: Second, 3D-CLM is employed to improve the system’s security and efficiency, allowing it to be used as

Keywords： Quaternion     Adaptive watermarking     Encryption     Fractional transform     Three-dimensional chaotic logistic map (3D-CLM    

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The function and regulation of OTU deubiquitinases

Jiansen Du, Lin Fu, Yingli Sui, Lingqiang Zhang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 542-563 doi: 10.1007/s11684-019-0734-4

Abstract: Post-translational modification of cellular proteins by ubiquitin regulates numerous cellular processesUbiquitin-mediated control over these processes can be reversed by deubiquitinases (DUBs), which removeubiquitin from target proteins and depolymerize polyubiquitin chains.

Keywords： ubiquitin     OTU deubiquitinases     structure     function     regulation    

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Heterologous expression of

Potter,Francis E. Nano

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 2, doi: 10.1007/s11783-017-0910-1

Abstract: Maximum growth rate of mutant was 0.083 h with 5% CO . Maximum biomass concentration of mutant was 3.697 g·L . mutant can tolerate gas aeration with 15% CO . Maximum specific activity of laminarinase was 4.325 U·mg dry mass. Optimal pH and temperature of laminarinase activity were 8.0 and 70°C. The gene for the catalytic domain of thermostable endo-β-1,3-glucanase (laminarinase) LamA was cloned from Thermotoga maritima MSB8 and heterologously expressed in a bioengineered Synechococcus sp. PCC 7002. The mutant strain was cultured in a photobioreactor to assess biomass yield, recombinant laminarinase activity, and CO2 uptake. The maximum enzyme activity was observed at a pH of 8.0 and a temperature of 70°C. At a CO2 concentration of 5%, we obtained a maximum specific growth rate of 0.083 h , a biomass productivity of 0.42 g·L ·d , a biomass concentration of 3.697 g·L , and a specific enzyme activity of the mutant strain of 4.325 U·mg dry mass. All parameters decreased as CO2 concentration increased from 5% to 10% and further to 15% CO2, except enzyme activity, which increased from 5% to 10% CO2. However, the mutant culture still grew at 15% CO2 concentration, as reflected by the biomass productivity (0.26 g·L ·d ), biomass concentration (2.416 g·L ), and specific enzyme activity (3.247 U·mg dry mass).

Keywords： PCC 7002     Thermotoga maritima     LamA gene     Endo-β-1     3-glucanase     CO2 fixation    

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Sustainability of metal recovery from E-waste

Biswajit Debnath, Ranjana Chowdhury, Sadhan Kumar Ghosh

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 6, doi: 10.1007/s11783-018-1044-9

Abstract:

Metal recovery techniques from electronic waste reported in literature.

Metal recovery processes followed in Industries from electronic waste.

Sustainability analysis of metal recovery processes from electronic waste.

Keywords： E-waste     Metal recovery     Metal Recovery from E-waste (MREW)     Sustainability    

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risks of heavy metals, polybrominated diphenyl ethers, and polychlorinated dibenzo-dioxins/furans at e-waste

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1679-z

Abstract:

● Heavy metals and organic toxins may persist in legacy sites for a long time.

Keywords： E-waste     Human health risk     Organ risk     Heavy metal toxicity     PBDE     PCDD/F    

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Title Author Date Type Operation

APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Journal Article

Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells

Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kaifeng Xu, Guangbiao Zhou

Journal Article

APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Journal Article

Identification of an E3 ligase-encoding gene

Yanfei Zhang, Xinchun Zhao, Yongchun Zhou, Min Wang, Guangbiao Zhou

Journal Article

mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?

Shi-Yong Sun

Journal Article

APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Baohua CHU, Jia SUN, Huan DANG, Ziqing MA, Shuang ZHAO, Qingmei GUAN, Xuewei LI

Journal Article

Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Journal Article

Design of GPRS Data Terminal Based on S3C2410

Sun Xueyong

Journal Article

A cooperative heterogeneous vehicular clustering framework for efficiency improvement

Iftikhar Ahmad, Rafidah Md Noor, Zaheed Ahmed, Umm-e-Habiba, Naveed Akram, Fausto Pedro García Márquez

Journal Article

Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

Collaborative Research Group, De-Pei LIU PhD, Lai-Yuan WANG PhD, Jing CHEN MD, MSc, Jiang HE MD, PhD, Cashell E.RAO PhD, Charles GU PhD, James E. HIXSON PhD, Chung-Shiuan CHEN MS8, Paul K.

Journal Article

A novel hybrid cryptosystem based on DQFrFT watermarking and 3D-CLM encryption for healthcare services

SOLIMAN, Fathi E.

Journal Article

The function and regulation of OTU deubiquitinases

Jiansen Du, Lin Fu, Yingli Sui, Lingqiang Zhang

Journal Article

Heterologous expression of

Potter,Francis E. Nano

Journal Article

Sustainability of metal recovery from E-waste

Biswajit Debnath, Ranjana Chowdhury, Sadhan Kumar Ghosh

Journal Article

risks of heavy metals, polybrominated diphenyl ethers, and polychlorinated dibenzo-dioxins/furans at e-waste

Journal Article